1321499-15-3

Basic information

• Product Name: 5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one
• Synonyms: 5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one
• CAS NO: 1321499-15-3
• Molecular Weight: 221.28
• Mol File: 1321499-15-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one(1321499-15-3)
• EPA Substance Registry System: 5-hydroxy-4-methyl-3-phenylsulfanyl-3-pyrrolin-2-one(1321499-15-3)

Safety Data

• Hazardous Substances Data: 1321499-15-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1321499-06-2 3-oxo-2-phenylsulfanyltetradecanamide 
• 78-98-8 2-oxopropanal 

Relevant articles and documents

Transformation of thiols to disulfides by epolactaene and its derivatives

In this paper we report a disulfide formation of thiols induced by epolactaene and its derivatives. We previously reported the disulfide formation of N-acetylcysteine methyl ester by epolactaene in a 1:1 MeOH/0.5 M NaHCO 3 aq solution. The present studies reveal that the disulfide formation proceeds under mild conditions such as in PBS at pH 7.3, suggesting that epolactaene may induce disulfide formation of cellular thiols. This compound induces the disulfide formation of several thiols in a 1:1 MeOH/0.5 M NaHCO3 aq solution at room temperature. Moreover, our results show that the acyl side-chain of epolactaene greatly influences the products of the reaction. We analyzed the reaction mechanism by using thiolysis products of epolactaene derivatives and propose a new reaction mechanism.