1321942-27-1Relevant articles and documents
Substituent-controlled reactivity in the Nazarov cyclisation of allenyl vinyl ketones
Marx, Vanessa M.,Stoddard, Rhonda L.,Heverly-Coulson, Gavin S.,Burnell, D. Jean
, p. 8098 - 8104 (2011/09/14)
Alkyl substitution α to the ketone of an allenyl vinyl ketone enhances Nazarov reactivity by inhibiting alternative pathways involving the allene moiety and through electron donation and/or steric hindrance. This substitution pattern also accelerates Naza