1322668-05-2

Upstream product

• 591-50-4 iodobenzene 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 3340-78-1 2-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 4712-55-4 diphenyl hydrogen phosphite 

Downstream Products

• 6772-51-6 2-phenyl-3,4-dihydroisoquinolin-1(2H)-one 
• 162334-78-3 2-phenylisoquinolin-1(2H)-one 

Relevant academic research and scientific papers

Electrochemical Cross-Dehydrogenative Coupling of N-Aryl-tetrahydroisoquinolines with Phosphites and Indole

A metal- and reagent-free, electrochemical cross-dehydrogenative coupling reaction of N-aryl-tetrahydroisoquinolines with phosphites and indole is developed. This method provides an environmentally benign and simple approach for the construction of C–P an

Photoelectrochemical cell for P-H/C-H cross-coupling with hydrogen evolution

Photoelectrochemistry enables the formation of a variety of active intermediates for organic synthesis in an environmentally friendly manner. Herein, a photoelectrochemical cell is fabricated to realize activation of P-H/C-H bonds for cross-coupling hydro

Photo-induced thiol coupling and C-H activation using nanocrystalline lead-halide perovskite catalysts

The use of photon energy to promote chemical transformations offers versatile control of reaction kinetics and progress. Over the past decade, many photoactive transition-metal complexes and organic chromophores were developed to catalyze chemical transformations, enabling a myriad of reactions and compounds that were previously inaccessible via traditional synthetic methods. Here, we demonstrate the photocatalytic oxidative coupling of organic thiols using cesium lead halide perovskite nanocrystals as photocatalysts. The photo-catalyzed thiol coupling reactions selectively produced symmetric and unsymmetrical disulfides in high yields (68-96% isolated yields). Additionally, we discovered a perovskite-catalyzed phosphonylation of tertiary amines via visible-light-mediated cross-dehydrogenative coupling reaction, and obtained good isolated yields (50-96%). The variety of visible-light-induced photocatalytic processes that perovskite nanocrystals are capable of, coupled with their facile preparation, easily tunable redox potentials, high catalytic efficiency and reusability, presents great opportunities for their future applications in green and sustainable organic synthesis.

Cationic Polycarbazole Networks as Visible-Light Heterogeneous Photocatalysts for Oxidative Organic Transformations

Photoredox catalysis has aroused great interest from chemists, as it offers a powerful tool for organic synthesis. Cationic polycarbazole networks (CPOP-28 and CPOP-29) were prepared via simple oxidative coupling reaction and applied as heterogeneous photocatalysts for a wide range of oxidative organic transformations, including oxidation of sulfides, hydroxylation of arylboronic acids, and cross-dehydrogenative coupling reactions, in the presence of visible light and air. Remarkably, photocatalytic activities are enhanced by ingenious introduction of trifluoromethyl groups to the polymeric network CPOP-29. The effects of the trifluoromethyl group on photocatalytic activities were elucidated in terms of photophysical and electrochemical properties. The appealing photocatalytic performance of the trifluoromethylated polymer is ascribed to superior light-absorption ability, longer fluorescence lifetime, and stronger oxidative capability. In addition, the photocatalysts showed good recyclability and could be reused after a simple separation workup.

The singlet excited state of BODIPY promoted aerobic cross-dehydrogenative-coupling reactions under visible light

In contrast to previous studies, we disclose for the first time that the singlet excited state (1PS?) of BODIPY rather than the triplet excited state (3PS?) can drive C-H bond activation to form C-C and C-P bonds smoothly, which offers new methods to promote organic transformation under visible light irradiation.

Catalytic amounts of triarylaminium salt initiated aerobic oxidative coupling of N-aryl tetrahydroisoquinolines

A novel stable radical cation triarylaminium salt able to induce aerobic oxidative α-C-H functionalization of tertiary amines in catalytic amounts has been developed. The reaction is performed in the absence of any other additives under mild conditions an

Direct oxidative phosphonylation of amines under metal-free conditions

Direct oxidation coupling of tertiary amines and dialkyl- or diphenyl-substituted phosphonates was developed. The reaction was mediated by DDQ under room temperature. Various phosphonates and N-aryl tetrahydroisoquinolines were tolerated in this reaction,

Photoredox catalyzed C-P bond forming reactions - Visible light mediated oxidative phosphonylations of amines

A visible light mediated, carbon-phosphorus bond forming reaction has been developed. With the use of a readily available photoredox catalyst, α-amino phosphonates were obtained in good yields under mild reaction conditions. The Royal Society of Chemistry