132282-01-0

Upstream product

• 132282-00-9 (E)-3-[(2S,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-acrylic acid benzyl ester 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 
• 119588-68-0 (E)-3-[(2S,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propenal 

Downstream Products

• 132282-10-1 3-Hydroxy-3-[(2S,4S,5R)-4-methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propionic acid 
• 132282-02-1 (S)-3-Hydroxy-3-[(2S,4S,5R)-4-methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propionic acid methyl ester 
• 132282-12-3 (R)-3-Hydroxy-3-[(2S,4S,5R)-4-methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

SYNTHESIS OF ENANTIOMERIC PURE INTERMEDIATE FOR THE LACTONE PORTION OF COMPACTIN AND MEVINOLIN.

A diastereo and enantioselective synthesis of compound 11, a potential useful intermediate for the lactone portion of mevinolin and compactin, was developed.Our strategy is based on the high stereoselective Michael addition of alkoxide to chiral norephedr