132292-27-4

Upstream product

• 132292-26-3 1-carboxy-1'-hydroxy-1,1':4',1''-tercyclohexan-4-one ethylene ketal 
• 92-68-2 4-cyclohexylcyclohexanone 
• 66500-55-8 cyclohexanone-4-carboxylic acid ethyleneacetal 

Downstream Products

• 132292-30-9 cis-1,1':4',1''-tercyclohexan-4-one 
• 132292-31-0 trans-1,1':4',1-tercyclohexyl-4-one 
• 112649-02-2 4-[4-(cyclohexyl)cyclohexyliden]-1-cyclohexanone 

Relevant academic research and scientific papers

Synthesis of tercyclohexanones

A synthetic route to tercyclohexanones is described in which alkylation of 4-cyclohexylcyclohexanone with the dianion of 4,4-(ethylenedioxy)cyclohexanecarboxylic acid gives 1-carboxy-1'-hydroxyl-1,1':4',1''-tercyclohexan-4-one ethylene ketal. Decarboxylative dehydration of the latter followed by hydrolysis of the ketal gives 4-(4'-cyclohexylcyclohexylidene)cyclohexanone. Hydrogenation of this compound gives cis- and trans-1,1':4',1''-tecyclohexan-4-one, the latter of which is correlated with authentic trans-1,1':4',1''-tercyclohexane.