1323264-00-1

Basic information

• Product Name: 2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}propane-1,2-diol
• Synonyms: 2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}propane-1,2-diol
• CAS NO: 1323264-00-1
• Molecular Weight: 352.815
• Mol File: 1323264-00-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}propane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}propane-1,2-diol(1323264-00-1)
• EPA Substance Registry System: 2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}propane-1,2-diol(1323264-00-1)

Safety Data

• Hazardous Substances Data: 1323264-00-1(Hazardous Substances Data)

Upstream product

• 108545-00-2 4-chloro-2,6-dimethoxyphenol 
• 180092-32-4 [2-(1-methylethenyl)phenyl]methyl alcohol 
• 2675-80-1 1,2,3-trimethoxy-5-chlorobenzene 
• 1323263-89-3 5-chloro-1,3-dimethoxy-2-{[2-(1-methylethenyl)phenyl]methoxy}benzene 

Downstream Products

• 1323264-09-0 2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}-2-hydroxypropanoic acid 
• 1323264-24-9 N-{1-[(6-aminopyridin-2-yl)methyl]piperidin-4-yl}-2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}-2-hydroxypropanamide 

Relevant articles and documents

Synthesis of antagonists of muscarinic (M3) receptors

Several α-hydroxyamides with (2,6-dialkoxyphenoxy)methyl substituents have been prepared and their activities as antagonists of the M3 muscarinic receptor in guinea pig ileum have been evaluated. N-{1-[(Phenyl)methyl]piperidin-4-yl}-2-{2-[(2,6-dimethoxyphenoxy)-methyl]phenyl} -2-hydroxypropanamide and N-(1-[{6-amino-4-[(1-propylpiperidin-4-yl)methyl]- pyridin-2-yl}methyl]piperidin-4-yl)-2-cyclopentyl-2-hydroxy-2-phenylacetamide were the most potent compounds prepared, the micromolar potency of the latter indicating that it may be worth further investigation.