108545-00-2

Basic information

• Product Name: 2,6-DIMETHOXY-4-CHLOROPHENOL
• Synonyms: 2,6-DIMETHOXY-4-CHLOROPHENOL;4-Chloro-2,6-dimethoxyphenol
• CAS NO: 108545-00-2
• Molecular Formula: C₈H₉ClO₃
• Molecular Weight: 188.609
• Mol File: 108545-00-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-DIMETHOXY-4-CHLOROPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIMETHOXY-4-CHLOROPHENOL(108545-00-2)
• EPA Substance Registry System: 2,6-DIMETHOXY-4-CHLOROPHENOL(108545-00-2)

Safety Data

• Hazardous Substances Data: 108545-00-2(Hazardous Substances Data)

Usage

Chemical type

chlorinated phenol derivative

Functional groups

two methoxy groups

Common uses

disinfectant, antiseptic

Usage in products

soaps, creams, topical medications

Antimicrobial properties

effective against bacteria and fungi

Toxicity

can be toxic and irritate skin and respiratory system in high concentrations

Environmental impact

potential for harm, proper disposal important

Upstream product

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Downstream Products

• 1323264-24-9 N-{1-[(6-aminopyridin-2-yl)methyl]piperidin-4-yl}-2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}-2-hydroxypropanamide 
• 1323264-09-0 2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}-2-hydroxypropanoic acid 
• 1323264-00-1 2-{2-[(4-chloro-2,6-dimethoxyphenoxy)methyl]phenyl}propane-1,2-diol 
• 1323263-89-3 5-chloro-1,3-dimethoxy-2-{[2-(1-methylethenyl)phenyl]methoxy}benzene 

Relevant articles and documents

Synthesis of antagonists of muscarinic (M3) receptors

Several α-hydroxyamides with (2,6-dialkoxyphenoxy)methyl substituents have been prepared and their activities as antagonists of the M3 muscarinic receptor in guinea pig ileum have been evaluated. N-{1-[(Phenyl)methyl]piperidin-4-yl}-2-{2-[(2,6-dimethoxyphenoxy)-methyl]phenyl} -2-hydroxypropanamide and N-(1-[{6-amino-4-[(1-propylpiperidin-4-yl)methyl]- pyridin-2-yl}methyl]piperidin-4-yl)-2-cyclopentyl-2-hydroxy-2-phenylacetamide were the most potent compounds prepared, the micromolar potency of the latter indicating that it may be worth further investigation.

Preparation of chlorosyringols and chloropyrogallols - Components of pulp bleaching effluents

The preparation and properties of chlorosyringols and chloropyrogallols, components of pulp bleaching effluents, and their acetates are given. The compounds are obtained mainly by direct chlorination of both phenols or of syringol acetate with various chlorinating reagents. 5-Chloropyrogallol and 4,5-dichloropyrogallol were the products of demethylation of 5-chloro-3-methoxycatechol acetate and 4,5-dichloro-3-methoxycatechol acetate, respectively. The acetates of all ten chloro compounds were separated by gas chromatography. Electron impact mass spectra and 1H and 13C NMR data for the acetates are given.