13233-85-7

Upstream product

• 4230-26-6 6-chloro-9-(4-nitrophenylmethyl)-9H-purine 
• 124-40-3 dimethyl amine 

Downstream Products

• 112089-10-8 9-(4-Aminobenzyl)-6-(dimethylamino)-9H-purine 
• 119805-75-3 2-Amino-N-[4-(6-dimethylamino-purin-9-ylmethyl)-phenyl]-3-phenyl-propionamide 
• 119805-55-9 9-(4-carbobenzoxyglycylamidobenzyl)-6-dimethylamino-9H-purine 
• 119805-68-4 {1-[4-(6-Dimethylamino-purin-9-ylmethyl)-phenylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester 
• 119805-69-5 {1-[4-(6-Dimethylamino-purin-9-ylmethyl)-phenylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester 
• 119805-74-2 2-Amino-4-methyl-pentanoic acid [4-(6-dimethylamino-purin-9-ylmethyl)-phenyl]-amide; hydrochloride 
• 119805-72-0 2-Amino-N-[4-(6-dimethylamino-purin-9-ylmethyl)-phenyl]-acetamide; compound with acetic acid 

Relevant academic research and scientific papers

6-(Alkylamino)-9-benzyl-9H-purines. A New Class of Anticonvulsant Agents

Several 9-alkyl-6-substituted-purines were synthesized and tested for anticonvulsant activity against maximal electroshock-induced seizures (MES) in rats.Most compounds were prepared in three steps from 5-amino-4,6-dichloropyrimidine or in two steps via alkylation of 6-chloropurine.Potent anticonvulsant activity against MES resided in compounds that contain a benzyl substituent at the 9-position of 6-(methylamino)- or 6-(dimethylamino)purine.Among commonly used agents for control of seizures, this type of structure represents a new class of potent anticonvulsant agents.