132336-24-4Relevant academic research and scientific papers
Resin glycosides from Porana duclouxii
Ding, Wen-Bing,Zhang, Dai-Gui,Liu, Chun-Jie,Li, Guan-Hua,Li, You-Zhi
, p. 135 - 140 (2014)
A new intact resin glycoside (3) and two glycosidic acids (1 and 2), all having a common trisaccharide moiety and (11S)-hydroxytetradecanoic acid or (3S,11S)-dihydroxytetradecanoic acid as the aglycone, were obtained from the roots of Porana duclouxii. Their structures were elucidated by spectroscopic analyses and chemical correlations. These compounds represent the first examples of resin glycosides from the genus Porana.
Jalapinoside II, a bisdesmoside resin glycoside, and related glycosidic acids from the officinal jalap root (Ipomoea purga)
Bautista, Elihú,Fragoso-Serrano, Mabel,Pereda-Miranda, Rogelio
, p. 85 - 93 (2016/07/21)
Jalapinoside II, a macrocyclic bidesmoside resin glycoside with purgic acid C as its oligosaccharide core, was isolated by recycle preparative-scale HPLC from the MeOH-soluble extract of Ipomoea purga (Convolvulaceae), the officinal jalap root (“Rhizoma Jalapae”). This study also reports the complete NMR data assignment for purgic acid C and the structural elucidation of purgic acid D, both glycosidic acids were isolated, in conjunction with previously known purgic acids A and B, under saponification of the MeOH-soluble resin glycosides. HPLC and 13C NMR profiles were used as analytical tools for the authentication of the commercialized Mexican scammony resin. Reversal factor of multidrug resistance by the non-cytotoxic jalapinoside II was evaluated in vinblastine-resistant human breast carcinoma cells (RFMCF-7/Vin+ > 1906).
