132350-77-7

Upstream product

• 100-42-5 styrene 
• 15431-30-8 methyl 2-diazo-2-nitroacetate 
• 2483-57-0 methyl 2-nitroacetate 

Downstream Products

• 1036637-47-4 methyl 2-nitro-4-phenyl-4-pyrrolidin-1-ylbutanoate 
• 1036637-48-5 methyl 2-nitro-4-phenyl-4-(piperidin-1-yl)butanoate 
• 1353673-84-3 methyl 4-((4-bromophenyl)amino)-2-nitro-4-phenylbutanoate 
• 1353673-87-6 methyl 2-nitro-4-phenyl-4-(2-phenylhydrazinyl)butanoate 
• 1353673-72-9 methyl 2-amino-4-phenyl-4-(phenylamino)butanoate 
• 1353673-70-7 N-(3-nitro-1-phenylpropyl)aminobenzene 
• 1353673-86-5 methyl 4-(indolin-1-yl)-2-nitro-4-phenylbutanoate 
• 1353673-85-4 methyl 4-morpholin-4-yl-2-nitro-4-phenylbutanoate 
• 1036637-34-9 methyl 4-[(2-bromophenyl)amino]-2-nitro-4-phenylbutanoate 
• 1036637-38-3 methyl 4-[methyl(phenyl)amino]-2-nitro-4-phenylbutanoate 

Relevant academic research and scientific papers

Hypervalent iodine(III) reagents as safe alternatives to α-nitro-α-diazocarbonyls

(Matrix presented) A cyclopropanation reaction involving iodonium ylides generated in situ allows for efficient preparation of substituted 1-nitro-1-carbonyl cyclopropanes. This robust cyclopropanation reaction can be performed in organic solvents, biphasic aqueous media, or under solvent-free conditions with alkene substrates. The iodonium ylides generated in situ display some surprising differences in reactivity when compared to α-nitro-α-diazocarbonyl compounds. They do not undergo O-H insertion reactions and exhibit reduced reactivity with certain alkenes.

NITROCYCLOPROPANES FROM NITRODIAZOMETHANES. PREPARATION AND REACTIVITY

Nitrodiazo compounds cyclopropanate electron rich alkenes in the presence of rhodium(II) acetate.The yields and diastereoselectivities are dependent on both the alkene and the nitrodiazo precursor.Nitrocyclopropanecarboxylates undergo ring opening, reduct