132408-61-8 Usage
Derivative of triazole
Yes
It is a derivative of the five-membered heterocyclic compound triazole, which contains three nitrogen atoms.
Pharmaceutical research and development
Building block
The compound is commonly used as a building block for the synthesis of various biologically active compounds in the pharmaceutical industry.
Potential applications
Antifungal and antimicrobial properties
It has been studied for its potential as an antifungal and antimicrobial agent, indicating possible uses in treating or preventing infections.
Chemical reactions
Used in various reactions
The compound is utilized in different chemical reactions, highlighting its versatility in organic chemistry.
Reagent in organic synthesis
Yes
It serves as a reagent in organic synthesis, further emphasizing its importance in chemical research and development.
Safety precautions
Harmful if in contact with skin or ingested
It is crucial to handle this compound with caution, as it can be harmful if it comes into contact with the skin or is ingested, necessitating proper safety measures during its use.
Check Digit Verification of cas no
The CAS Registry Mumber 132408-61-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,4,0 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 132408-61:
(8*1)+(7*3)+(6*2)+(5*4)+(4*0)+(3*8)+(2*6)+(1*1)=98
98 % 10 = 8
So 132408-61-8 is a valid CAS Registry Number.
132408-61-8Relevant articles and documents
Alkyl Substituent Effects on the Neutral Hydrolysis of 1-Acyl-(3-substituted)-1,2,4-triazoles in Highly Aqueous Reaction Media. The Importance of Solvation
Blokzijl, Wilfried,Blandamer, Michael J.,Engberts, Jan B. F. N.
, p. 1832 - 1837 (2007/10/02)
The importance of solvation in determining substituent effects of alkyl groups has been assessed in a quantitative study of the medium effects of ethanol and 1-propanol on the neutral hydrolysis of 18 1-acyl-(3-substituted)-1,2,4-triazoles in highly aqueous solutions.The dependence of the pseudo-first-order rate constants for hydrolysis on the molality of added cosolvent is analyzed in terms of pairwise Gibbs function interaction parameters and individual group contributions to the overall medium effect.It is found that the alkyl substituent effects depend on the presence of the cosolvent and that this medium dependence is different for different alkyl groups.In addition, the effect is sensitive to the position of the substituent and the overall hydrophobicity of the substrate.Alkyl substituent effects have also been examined for the acid-catalyzed hydrolysis of a series of 1-acyl-(3-substituted)-1,2,4-triazoles.The solvation dependence of alkyl substituent effects is discussed in terms of changes in hydration of the substrate during the activation process.
