96440-78-7

Basic information

• Product Name: 3-tert-butyl-1H-1,2,4-triazole
• Synonyms: 3-tert-butyl-1H-1,2,4-triazole;1H-1,2,4-triazole, 3-(1,1-dimethylethyl)-;3-tert-Butyl-4H-1,2,4-triazole;3-tert-butyl-2H-1,2,4-triazole
• CAS NO: 96440-78-7
• Molecular Formula: C6H11N3
• Molecular Weight: 125
• Mol File: 96440-78-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-tert-butyl-1H-1,2,4-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-tert-butyl-1H-1,2,4-triazole(96440-78-7)
• EPA Substance Registry System: 3-tert-butyl-1H-1,2,4-triazole(96440-78-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 96440-78-7(Hazardous Substances Data)

Usage

General Description

3-tert-butyl-1H-1,2,4-triazole is a heterocyclic compound with the chemical formula C7H12N3. It is a derivative of 1,2,4-triazole and contains a tert-butyl group. 3-tert-butyl-1H-1,2,4-triazole is commonly used as a corrosion inhibitor for metals, especially copper and its alloys. It has also been studied for its potential application as an antifungal and antibacterial agent. 3-tert-butyl-1H-1,2,4-triazole is stable under normal conditions and is soluble in organic solvents. However, it should be handled with care as it may be irritating to the skin, eyes, and respiratory system.

Upstream product

• 3282-30-2 pivaloyl chloride 
• 79-19-6 thiosemicarbazide 
• 132408-63-0 1-ethanoyl-3-tert-butyl-1,2,4-triazole 

Downstream Products

• 132408-63-0 1-ethanoyl-3-tert-butyl-1,2,4-triazole 
• 132408-61-8 1-(3-tert-Butyl-[1,2,4]triazol-1-yl)-ethanone 
• 146858-36-8 5-bromo-3-t-butyl-1H-1,2,4-triazole 

Relevant articles and documents

SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.

Remarkably Distinctive Recognition of α-Alanine and α-Phenylalanine during the Water-Catalyzed Hydrolysis of an Activated Amide

The rate of the water-catalyzed hydrolysis of three activated amides in aqueous solution is significantly retarded by small amounts of α-phenylalanine as compared with the rate acceleration induced by other common α-amino acids not containing a benzyl group in their side chain.These contrasting effects emphasize the large hydrophobicity of α-phenylalanine and are of relevance for a better quantitative understanding of protein folding and molecular recognition processes involving proteins.