132424-10-3

Usage

Uses

Used in Pharmaceutical Industry:
N-methyl-N-(3-phenoxypropyl)amine is used as a reactant in organic syntheses for the production of pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, N-methyl-N-(3-phenoxypropyl)amine serves as a building block for the synthesis of various agrochemicals, aiding in the creation of effective pest control and crop protection products.
Used in Specialty Chemicals Industry:
N-methyl-N-(3-phenoxypropyl)amine is utilized as a key component in the synthesis of specialty chemicals, which have diverse applications across various industries, such as coatings, adhesives, and fragrances.
As a Hazardous Substance:
Due to its hazardous nature, N-methyl-N-(3-phenoxypropyl)amine requires careful handling and storage to ensure safety and minimize environmental impact.

InChI:InChI=1/C10H15NO/c1-11-8-5-9-12-10-6-3-2-4-7-10/h2-4,6-7,11H,5,8-9H2,1H3

Upstream product

• 588-63-6 3-phenoxypropyl bromide 
• 108-95-2 phenol 
• 74-89-5 methylamine 

Downstream Products

• 1146681-11-9 2-(2,4-difluorophenyl)-3-[methyl-(3-phenoxypropyl)amino]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol 
• 228567-52-0 11β-fluoro-7α-{5-[methyl-(3-phenoxy-propyl)-amino]-pentyl}-estra-1,3,5(10)-triene-3,17β-diol 

Relevant academic research and scientific papers

Synthesis of Medium-Ring-Sized Benzolactams by Using Strong Electrophiles and Quantitative Evaluation of Ring-Size Dependency of the Cyclization Reaction Rate

Benzolactams with medium-sized rings were synthesized via the electrophilic aromatic substitution reaction of carbamoyl cations (R1R2N+═C═O) in good to high yields without dilution. These reactions were utilized to quantitatively examine the extent of retardation of medium-sized ring formation, compared to five- or six-membered ring formation. The order of reaction rates of formation of cyclic benzolactams is six- > five- > seven- > eight- > nine-membered ring at 25 °C. The present reaction provides a route to eight- A nd nine-membered benzolactams.

Design, synthesis, and antifungal activity of novel conformationally restricted triazole derivatives

A series of new triazole derivatives were designed and synthesized on the basis of the active site of lanosterol 14α-demethylase from Candida albicans (CACYP51). 2-(2,4-Difluorophenyl)-3-(methyl-(3-phenoxyalkyl)amino)-1- (1H-1,2,4-triazol-1-yl)propan-2-ols show excellent in-vitro activity against most of the tested pathogenic fungi. The MIC80 value of compound 8a against Candida albicans is 0.01 μM, which provides a good starting template for further structural optimization. The binding modes of the designed compounds were investigated by flexible molecular docking. The compounds interacted with CACYP51 through hydrophobic, van-der-Waals, and hydrogenbonding interactions.

11BETA-HALOGEN-7ALPHA-SUBSTITUTED ESTRATRIENES, METOD FOR PRODUCING PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11BETA-HALOGEN-7ALPHA- SUBSTITUTED ESTRATRIENES AND USE OF THE SAME FOR PRODUCING MEDICAMENTS

This invention describes the new 11β-halogen-7α-substituted estratrienes of general formula I in which R11 is a fluorine or chlorine atom, and the other substituents have the meanings that are explained in more detail in the description. The compounds have antiestrogenic properties or tissue-selective estrogenic properties and are suitable for the production of pharmaceutical agents.