1324498-95-4Relevant academic research and scientific papers
Iodoarene-catalyzed cyclizations of N-propargylamides and -amidoketones: Synthesis of 2-oxazolines
Kamouka, Somaia,Moran, Wesley J.
supporting information, p. 1823 - 1827 (2017/09/27)
Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of -amidoketones. These are proposed to proceed through differ
Continuous flow Sonogashira C-C coupling using a heterogeneous palladium-copper dual reactor
Tan, Li-Min,Sem, Zhi-Yu,Chong, Wei-Yuan,Liu, Xiaoqian,Hendra,Kwan, Wei Lek,Lee, Chi-Lik Ken
supporting information, p. 65 - 67 (2013/03/28)
We report the development of a heterogeneous catalyst system on continuous flow chemistry. A palladium (Pd) coated tubular reactor was placed in line with copper (Cu) tubing using a continuous flow platform, and a Sonogashira C-C coupling reaction was used to evaluate the performance. The reactions were favorably carried out in the Cu reactor, catalyzed by the traces of leached Pd from the Pd reactor. The leached Pd and Cu were trapped with a metal scavaging resin at the back-end of the continuous flow system, affording a genuine approach toward green chemistry.
