132452-44-9Relevant academic research and scientific papers
Synthesis and Pharmacological Evaluation of Hexahydrofluorenamines as Noncompetitive Antagonists at the N-Methyl-D-aspartate Receptor
Hays, Sheryl J.,Novak, Perry M.,Ortwine, Daniel F.,Bigge, Christopher F.,Colbry, Norman L.,et al.
, p. 654 - 670 (2007/10/02)
The noncompetitive (PCP) site of the N-methyl-D-aspartate (NMDA) receptor complex has been implicated in a number of pathologies, including the etiology of ischemic stroke.Recent testing has shown that cis-1,2,3,4,9,9a-hexahydro-N-methyl-4aH-fluoren-4a-am
Polycyclic amines useful as cerebrovascular agents
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, (2008/06/13)
A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed.
