132454-51-4Relevant articles and documents
SYNTHESIS OF OXETANOCIN
Wilson, F. X.,Fleet, G. W. J.,Vogt, K.,Wang, Y.,Witty, D. R.,et al.
, p. 6931 - 6934 (2007/10/02)
A low yield synthesis of oxetanocin and its α-epimer by reaction of adenine with a protected 3-hydroxymethyl-2-chlorooxetane is described; attempts to synthesise other C-2'alkyl analogues of oxetanocin by analogous reactions indicate a limitation of this strategy for the synthesis of oxetane nucleosides.An intermediate for the synthesis of C-nucleoside analogues of oxetanocin is reported.