132454-50-3Relevant articles and documents
Synthesis of (t-2-Benzyloxymethyl-t-3-hydroxy-r-1-methoxycarbonyl)-tetrahydrofuran from an arabino-Lactone Triflate with K2CO3-MeOH
Izawa, Takao,Nakayama, Kumiko,Nishiyama, Shigeru,Yamamura, Shosuke,Kato, Kuniki,Takita, Tomohisa
, p. 3003 - 3004 (2007/10/02)
The arabino-lactone triflate 4 reacts with K2CO3 in MeOH to give the oxetane ester 5 and the tetrahydrofuran ester 6 in a ratio dependent upon the reaction temperature.
SYNTHESIS OF OXETANOCIN
Wilson, F. X.,Fleet, G. W. J.,Vogt, K.,Wang, Y.,Witty, D. R.,et al.
, p. 6931 - 6934 (2007/10/02)
A low yield synthesis of oxetanocin and its α-epimer by reaction of adenine with a protected 3-hydroxymethyl-2-chlorooxetane is described; attempts to synthesise other C-2'alkyl analogues of oxetanocin by analogous reactions indicate a limitation of this strategy for the synthesis of oxetane nucleosides.An intermediate for the synthesis of C-nucleoside analogues of oxetanocin is reported.