132486-36-3

Upstream product

• 629-11-8 1,6-hexanediol 
• 1438-14-8 2-isopropyloxirane 
• 1822-00-0 trimethylsilylmethyllithium 
• 765-03-7 1-dodecyne 
• 4352-44-7 1-cyclohexylprop-2-en-1-ol 

Downstream Products

• 1606-47-9 isopropyl vinyl ketone 
• 109787-42-0 (E)-<<2-<<1-(1-methylethyl)-2-propenyl>oxy>-1-propenyl>sulfonyl>benzene 
• 109787-41-9 [2-(1-Isopropyl-allyloxy)-prop-2-ene-1-sulfonyl]-benzene 
• 94225-55-5 (1-Isopropyl-allyloxymethyl)-carbamic acid benzyl ester 
• 128950-60-7 3-(benzyloxy)-4-methylpent-1-ene 
• 193558-97-3 [(E)-3-(1-Isopropyl-allyloxy)-propenyl]-benzene 
• 926-56-7 4-methyl-1,3-pentadiene 
• 763-30-4 2-methyl-1,4-pentadiene 
• 1118-58-7 1,3-Dimethyl-1,3-butadien 
• 847832-77-3 1-chloro-2-(1-isopropyl-allyloxy)-4-methyl-benzene 

Relevant academic research and scientific papers

The reactivity of epoxides with lithium 2,2,6,6-tetramethylpiperidide in combination with organolithiums or grignard reagents

(Chemical Equation Presented) The scope and limitations of lithium 2,2,6,6-tetramethylpiperidide (LTMP)-modified reductive alkylation of epoxides is detailed. A variety of organolithiums are added to terminal and 2,2-disubstituted epoxides in the presence of LTMP to generate alkenes in a completely regio- and highly stereoselective manner. Arylated alkenes, dienes, allylsilanes, and enynes are accessed using this procedure. The methodology is applied in the synthesis of the roller leaf moth pheromone, (3E,5Z)-dodecadienyl acetate. The corresponding reaction without LTMP has also been examined, and a study using deuterated epoxides provides insight into the mechanism. In the presence of LTMP, Grignard reagents are also shown to produce E-alkenes directly from epoxides.

Cyclodehydration of some 1,n-diols catalysed by sulfated zirconia

Sulfated zirconia, a solid acid is found to be a good catalyst in the cyclodehydration of several diols.