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Usage

Uses

Used in Pharmaceutical Development:
N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]-Urea is used as a precursor in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs. Its unique molecular structure may offer specific binding affinities or interactions with biological targets, which could be leveraged for therapeutic purposes.
Used in Agrochemical Development:
In the agrochemical industry, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]-Urea is used as a building block in the creation of new agrochemicals. Its properties may be harnessed to develop compounds that can effectively control pests or diseases in agriculture, potentially increasing crop yields and reducing losses.
Further research and investigation are necessary to fully understand the specific properties and potential uses of N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]-Urea, as its current applications are based on its structural characteristics and the possibilities they present in the fields of medicinal and agrochemical chemistry.

Upstream product

• 16588-74-2 3,5-ditrifluoromethylisocyanate 
• 56-54-2 quinidine 
• 287979-82-2 (R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanamine 
• 56-54-2 quinindine 
• 287979-82-2 9-amino-9-deoxyepiquinidine 
• 56-54-2 quinine 

Relevant academic research and scientific papers

Induction of Axial Chirality in 8-Arylquinolines through Halogenation Reactions Using Bifunctional Organocatalysts

The enantioselective syntheses of axially chiral heterobiaryls were accomplished through the aromatic electrophilic halogenation of 3-(quinolin-8-yl)phenols with bifunctional organocatalysts that control the molecular conformations during successive halogenations. Axially chiral quinoline derivatives, which have rarely been synthesized in an enantioselective catalytic manner, were afforded in moderate-to-good enantioselectivities through bromination, and an analogous protocol also enabled enantioselective iodination. In addition, this catalytic reaction, which allows enantioselective control through the use of mono-ortho-substituted substrates, allowed the asymmetric synthesis of 8-arylquinoline derivatives bearing two different halogen groups in high enantioselectivities.

Asymmetric chroman synthesis via an intramolecular oxy-Michael addition by bifunctional organocatalysts

Cinchona-alkaloid-urea-based bifunctional organocatalysts facilitate the catalytic asymmetric synthesis of chroman derivatives via an intramolecular oxy-Michael addition reaction. Phenol derivatives bearing an easily available (E)-α,β-unsaturated ketone or a thioester moiety are useful substrates for the title transformation. This method represents a facile synthesis of various optically active 2-substituted chromans in high yield. The Royal Society of Chemistry.

Asymmetric indoline synthesis via intramolecular aza-Michael addition mediated by bifunctional organocatalysts

A novel method for the asymmetric synthesis of 2-substituted indolines, employing bifunctional amino(thio)urea catalysts, was developed. The reaction proceeded via an intramolecular aza-Michael addition mediated by activation through hydrogen bonding. The

Enantioselective organocatalytic aryloxylation of β-keto esters

An efficient enantioselective aryloxylation of cyclic β-keto esters with a selection of substituted o-quinones catalyzed by a bifunctional cinchona alkaloid derivative, giving entry to tricyclic dioxin adducts with high enantio- and diastereoselectivity, is described. Georg Thieme Verlag Stuttgart - New York.