287979-82-2

Basic information

• Product Name: 9-Amino(9-deoxy)epi-quinidine trihydrochloride
• Synonyms: 9-Amino(9-deoxy)epi-quinidine trihydrochloride;(9R)-9-amine- 6'-methoxy-Cinchonan;(9R)-6'-Methoxy-cinchonan-9-amine Trihydrochloride,99%e.e.
• CAS NO: 287979-82-2
• Molecular Formula: C₂₀H₂₅N₃O
• Molecular Weight: 323.432
• Mol File: 287979-82-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 484.8±40.0 °C(Predicted)
• Appearance: /
• Density: 1.18±0.1 g/cm3(Predicted)
• PKA: 9.42±0.70(Predicted)
• CAS DataBase Reference: 9-Amino(9-deoxy)epi-quinidine trihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Amino(9-deoxy)epi-quinidine trihydrochloride(287979-82-2)
• EPA Substance Registry System: 9-Amino(9-deoxy)epi-quinidine trihydrochloride(287979-82-2)

Safety Data

• Hazardous Substances Data: 287979-82-2(Hazardous Substances Data)

Usage

General Description

9-Amino(9-deoxy)epi-quinidine trihydrochloride is a chemical compound commonly used as an antiarrhythmic drug. It is a derivative of quinidine, which acts as a potent blocker of the cardiac delayed rectifier potassium channel. 9-Amino(9-deoxy)epi-quinidine trihydrochloride is typically administered in the form of its trihydrochloride salt and has been extensively studied for its pharmacological properties in the treatment of various cardiac-related conditions. It is also utilized in research settings to investigate the effects of the compound on cardiac electrophysiology and arrhythmia mechanisms. Overall, 9-Amino(9-deoxy)epi-quinidine trihydrochloride is an important chemical compound with potential therapeutic applications in the field of cardiology and cardiovascular research.

Upstream product

• 1608182-10-0 C₂₉H₃₁N₃O 

Downstream Products

• 1155843-55-2 (9-deoxy)epiquinidine isothiocyanate 
• 1155843-50-7 N-[(9R)-6'-methoxycinchonan-9-yl]-N'-(9-phenylfluoren-9-yl)thiourea 
• 1155843-52-9 N-[(9R)-6'-methoxycinchonan-9-yl]-N'-[tris(3,5-dimethylphenyl)methyl]thiourea 
• 1155843-51-8 N-[(9R)-6'-methoxycinchonan-9-yl]-N'-tritylthiourea 
• 1155843-48-3 N-benzhydryl-N'-[(9R)-6'-methoxycinchonan-9-yl]thiourea 
• 1266571-99-6 1-cyclohexyl-3-((R)-(6-methoxyquinolin-4-yl)((2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)-thiourea 
• 1253115-31-9 3-(benzylamino)-4-(((1R)-(6-methoxyquinolin-4-yl)((2S,4S,5S)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione 
• 1326239-56-8 C₂₉H₂₈F₆N₄O₂ 
• 18797-90-5 C₂₀H₂₅N₃O*3ClH 
• 1155843-55-2 C₂₁H₂₃N₃OS 
• 1313052-77-5 C₂₉H₃₄N₄O₂S 
• 1608117-08-3 C₂₉H₃₄N₄O₂S 
• 852913-25-8 1-(3,5-bis(trifluoromethyl)phenyl)-3-((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea 

Relevant articles and documents

Transfer of 1-alkenyl groups between secondary amines. Relative stability and reactivity of enamines from popular organocatalysts

Enamines from 3-methylbutanal and several Pro- and Phe-derived secondary amines were prepared in DMSO-d6, CD3CN, and CDCl 3. For the first time, the relative thermodynamic stabilities of these and other enamines were compared, and rapid exchanges of 1-alkenyl groups were demonstrated. Competition experiments showed that the most favored enamines (without significant steric inhibition of resonance) react more rapidly with electrophiles.