13264-03-4

Upstream product

• 13241-00-4 methyl 4-deoxy-α-D-xylo-hexopyranoside 
• 108-24-7 acetic anhydride 
• 19488-41-6 Methyl-2,3,6-tri-O-benzoyl-4-desoxy-α-D-xylo-hexopyranosid 
• 141020-13-5 Methyl-2,3,6-tri-O-benzoyl-4-O-phenoxythiocarbonyl-α-D-galactopyranosid 
• 3601-36-3 methyl 2,3,6-tri-O-benzoyl-α-D-galactopyranoside 

Downstream Products

• 849132-36-1 phenyl 2,3,6-tri-O-acetyl-4-deoxy-1-thio-β-D-xylo-hexoside 
• 114942-44-8 2,4-dinitrophenyl-2,3,6-tri-O-acetyl-4-deoxy-β-D-xylo-hexopyranoside 

Relevant academic research and scientific papers

From glycoside hydrolases to thioglycoligases: The synthesis of thioglycosides

The treatment of various glycosyl acceptors, each containing a reactive thiol group, with the appropriate glycosyl donor and a glycoside hydrolase or glycosynthase, failed to yield any thioglycosides - only the products of O-glycosylation were formed. However, thioglycosides were formed when a thioglycoligase was used to mediate the reaction between acceptor and donor. In fact, pyranose acceptors possessing a thiol group at C3, C4 or C6 (but not C2) were all capable of conversion into thioglycosides. Some comment is given regarding the mechanism of the various processes.