1327310-96-2

Upstream product

• 2700-22-3 Benzylidenemalononitrile 
• 33512-02-6 3-phenyl-2,2-oxiranedicarbonitrile 
• 140-28-3 N,N'-Dibenzylethylenediamine 
• 1590449-58-3 N-benzoyl-O-(α-bromo-α-phenylacetyl)-L-threonine isopropyl ester 
• 1417715-05-9 O,O'-di(α-bromo-α-phenylacetyl)-N,N,N',N'-tetramethyl-L-tartaric diamide 
• 1417715-03-7 O,O'-di(α-bromo-α-phenylacetyl)-L-tartaric acid diisopropyl ester 
• 1319189-53-1 C₁₈H₂₃BrO₆ 
• 205748-19-2 (R,S)-2-Bromo-2-phenylacetic acid (R)-pantolactone ester 
• 2912-62-1 α-chlorophenylacetyl chloride 
• 1327310-57-5 2-chloro-2-phenylacetic acid (R)-pantolactone ester 
• 1327310-45-1 (2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate 
• 1192307-86-0 (2-methoxy-2-oxo-(S)-1-phenylethyl) α-bromophenylacetate 
• 4870-65-9 2-bromophenylacetic acid 
• 902778-26-1 1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-O-yl α-bromo-α-phenylacetate 

Relevant academic research and scientific papers

Stereoselective Substitution of Configurationally Labile α-Bromo Arylacetates with Amines and Azlactones by L -Threonine-Mediated Crystallization-Induced Dynamic Resolution

We developed a highly stereoselective C-N and C-C bond-forming reaction by carrying out a crystallization-induced dynamic resolution (CIDR) of α-bromo arylacetates followed by a stereoselective substitution reaction with an amine or azlactone nucleophile. Applications of this synthetic method to the preparation of highly enantioenriched nitrogen-containing six-membered heterocycles and α,β-disubstituted aspartates are also presented.

Asymmetric Epoxidation of Alkylidenemalononitriles: Key Step for One-Pot Approach to Enantioenriched 3-Substituted Piperazin-2-ones

The first enantioselective epoxidation of readily available alkylidenemalononitriles has been developed by using a multifunctional cinchona derived thiourea as the organocatalyst and cumyl hydroperoxide as the oxidant. A new simple one-pot asymmetric epox

Dynamic resolution of α-halo chiral esters for the synthesis of 3-substituted piperazin-2-ones

Dynamic resolution of α-halo esters derived from five chiral alcohols has been investigated in nucleophilic substitution with ethylenediamine nucleophiles. Stereoselective substitution of α-halo esters and following spontaneous cyclization provide a pract