13274-75-4

Upstream product

• 13274-45-8 4-(p-nitrophenyl)urazole 
• 13274-47-0 N-{[(4-nitrophenyl)carbamoyl]amino}ethoxyformamide 
• 622-58-2 p-Tolylisocyanate 
• 35580-58-6 C₁₁H₁₅N₃O₃ 
• 79491-05-7 4-(4-methylphenyl)-1,2,4-triazolidine-3,5-dione 

Relevant academic research and scientific papers

Investigating Bicyclobutane-Triazolinedione Cycloadditions as a Tool for Peptide Modification

Acyl bicyclobutanes are shown to engage in strain-promoted cycloaddition reactions with a diverse array of triazolinedione reagents. The synthesis of an orthogonally protected urazole building block enabled the facile preparation of amino acid- and peptid

N2O4 chemisorbed onto n-propylsilica kryptofix 21 and kriptofix 22 as two new functional polymers for the fast oxidation of urazoles and 1,4-dihydropyridines

3-Chloropropylsilica was reacted with Kriptofix 21 or 22 in the presence of triethylamine to form N-propylsilica Kryptofix 21 and Kriptofix 22. Then N 2O4 was added to each of these polymers to chemisorb onto cavity of aza-crown ethers. These functionalized polymers were applied for the fast and simple oxidation of urazoles and 1,4-dihydropyridines, respectively.

Oxidation of urazoles to their corresponding triazolinediones using benzyltriphenylphosphonium nitrate

Benzyltriphenylphosphonium nitrate in the presence of AlCl3 oxidised 1,2,4-triazolidine-3,5-diones to the corresponding 4-substituted-1,2,4- triazole-3,5-diones.

Metal-Free oxidation of urazole and 1,4-dihydropyridine derivatives under mild and heterogeneous conditions by nitro urea, derived from urea nitrate, and silica sulfuric acid

Mild combination of nitro urea, derived from urea nitrate, and silica sulfuric acid (SiO2OSO3H) might act as an efficient oxidizing media, which could be able to oxidize different types of heterocyclic compounds including urazoles and 1,4-dihydropyridines. The process presented here is operationally simple, environmentally benign, and reactions have been mildly carried out in dichloromethane at room temperature.

Catalytic and efficient oxidation of urazole derivatives to their corresponding triazolinediones using ammonium nitrate and metal hydrogen sulfate as catalyst

Catalytic oxidation of a variety of urazoles to the triazolinediones via combination of NH4NO3 in the presence of a catalytic amount of aluminium hydrogen sulfate has been developed at room temperature in dichloromethane.

Supported nitric acid on silica gel and polyvinyl pyrrolidone (PVP) as an efficient oxidizing agent for the oxidation of urazoles and bis-urazoles

A method for the oxidation of a good range of urazoles and bis-urazoles to the corresponding triazolinediones by supported nitric acid on silica gel (SiO2-HNO3) and/or polyvinyl pyrrolidone (PVP-HNO3) is described. Reactions have been carried out heterogeneously at room temperature in dichloromethane with good to excellent yields.

Iodogen: A novel reagent for the oxidation of urazoles under heterogeneous conditions

Iodogen is employed as an efficient oxidizing agent for the conversion of urazoles and bis-urazoles into the corresponding 1,2,4-triazoles in good to excellent yields under mild heterogeneous conditions at room temperature. Georg Thieme Verlag Stuttgart.

Catalytic oxidation of urazoles and bis-urazoles to their corresponding triazolinediones using aluminium nitrate and a catalytic amount of silica sulfuric acid

A simple and efficient catalytic oxidation of urazoles and a bis-urazole to the corresponding triazolinediones by treatment with Al(NO3) 3.9H2O in the presence of a catalytic amount of silica sulfuric acid is described. A good range of urazole derivatives was selectively oxidized in CH2Cl2 at room temperature in good to excellent yields.