79491-05-7

Basic information

• Product Name: 1,2,4-Triazolidine-3,5-dione, 4-(4-methylphenyl)-
• CAS NO: 79491-05-7
• Molecular Formula: C9H9N3O2
• Molecular Weight: 191.189
• Mol File: 79491-05-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2,4-Triazolidine-3,5-dione, 4-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Triazolidine-3,5-dione, 4-(4-methylphenyl)-(79491-05-7)
• EPA Substance Registry System: 1,2,4-Triazolidine-3,5-dione, 4-(4-methylphenyl)-(79491-05-7)

Safety Data

• Hazardous Substances Data: 79491-05-7(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic compound

Structure

Contains a five-membered ring with three nitrogen atoms and two oxygen atoms

Potential applications

Pharmaceutical and agrochemical industries

Use

Building block for the synthesis of various organic compounds and drugs

Substituent

4-(4-methylphenyl) on the triazolidine-3,5-dione ring

Specific properties or reactivity

The 4-(4-methylphenyl) substituent could impart specific properties or reactivity to the compound

Suitability

For various chemical transformations and applications

Further research

May uncover additional potential uses and benefits of this chemical compound

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 106-49-0 p-toluidine 
• 4114-31-2 ethylhydrazine carboxylate 
• 622-58-2 p-Tolylisocyanate 
• 3848-42-8 O-(4-nitrophenyl)-N-(4-tolyl)carbamate 
• 35580-58-6 C₁₁H₁₅N₃O₃ 
• 110-21-4 hydrazodicarboxamide 
• 540-23-8 p-toluidine hydrochloride 

Downstream Products

• 1258974-68-3 C₃₁H₄₁N₃O₄Si 
• 1258974-34-3 C₂₂H₂₁N₃O₄ 
• 1354201-89-0 C₂₃H₂₃N₃O₅ 
• 96025-94-4 3,5-Dioxo-2-(9H-thioxanthen-9-ylio)-4-p-tolyl-1,2,4-triazolidin-1-id-10,10-dioxid 
• 96025-95-5 2-(10,11-Dihydro-5H-dibenzocyclohepten-5-ylio)-3,5-dioxo-4-p-tolyl-1,2,4-triazolidin-1-id 
• 96025-93-3 2-(9,10-Dihydro-10-oxo-9-anthracenylio)-3,5-dioxo-4-p-tolyl-1,2,4-triazolidin-1-id 
• 96025-92-2 3,5-Dioxo-2-(2-oxo-1,2-diphenylethylio)-4-p-tolyl-1,2,4-triazolidin-1-id 
• 96025-96-6 2-(Diphenylmethylio)-3,5-dioxo-4-p-tolyl-1,2,4-triazolidin-1-id 
• 13274-75-4 4-(4-nitrophenyl)-3H-1,2,4-triazole-3,5-dione 
• 72708-83-9 4-(4-Methylphenyl)-1,2,4-triazoline-3,5-dione 

Relevant articles and documents

One-pot and novel route for the synthesis of 4-substituted-1,2,4- triazolidine-3,5-diones

The efficient and one-pot synthesis of 4-substituted-1,2,4-triazolidin-3,5- dione derivatives (4-substituted urazoles) via combination of triphosgene, substituted anilines, and ethyl carbazate in the presence of cesium carbonate is presented.

A novel one-pot synthesis of 4-substituted 1,2,4-triazolidine-3,5-diones

A simple and one-pot pathway for the preparation of 4-substituted phenyl derivatives of triazolidindiones (urazoles), starting from aniline derivatives is reported. In these methods aniline derivatives were reacted with ethyl chloroformate, to give the corresponding carbamate derivatives. In the second step semicarbazide derivatives were prepared from these carbamates by reaction with ethyl carbazide. The cyclization reactions of the corresponding semicarbazides furnished triazolidindiones. All reactions were performed in one vessel without the isolation of reaction intermediates, such as carbamates and semicarbazides, and the final products were isolated in good yields. Georg Thieme Verlag Stuttgart.