132862-06-7Relevant academic research and scientific papers
Synthesis and quantitative structure-activity relationships of N-(1- benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective σ1 receptor ligands
Huang, Yunsheng,Hammond, Philip S.,Whirrett, Brian R.,Kuhner, Ross J.,Wu, Li,Childers, Steven R.,Mach, Robert H.
, p. 2361 - 2370 (1998)
A series of N-(1-benzylpiperidin-4-yl)phenylacetamide derivatives was synthesized and evaluated for affinity at σ1 and σ2 receptors. Most of these compounds showed a high affinity for σ1 receptors and a low to moderate aff
COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES
-
Page 28, (2010/02/08)
There are provided according to the invention, novel compounds of formula (I)wherein R, R, R, R, Rand Rare as defined in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
