132871-77-3

Basic information

• Product Name: 3-amino-2-tert-butyl-4(3H)-quinazolinone
• Synonyms: 3-amino-2-tert-butyl-4(3H)-quinazolinone
• CAS NO: 132871-77-3
• Molecular Formula: C12H15N3O
• Molecular Weight: 217.267
• Mol File: 132871-77-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-amino-2-tert-butyl-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-2-tert-butyl-4(3H)-quinazolinone(132871-77-3)
• EPA Substance Registry System: 3-amino-2-tert-butyl-4(3H)-quinazolinone(132871-77-3)

Safety Data

• Hazardous Substances Data: 132871-77-3(Hazardous Substances Data)

Upstream product

• 84540-62-5 methyl N-trimethylacetylanthranilate 
• 3282-30-2 pivaloyl chloride 
• 134-20-3 2-carbomethoxyaniline 

Relevant articles and documents

Asymmetric Synthesis of N-N Axially Chiral Compounds by Phase-Transfer-Catalyzed Alkylations

N-N axially chiral skeletons are significant structural motifs in natural products, pharmaceuticals, and functional materials. Herein we disclose a method for the asymmetric synthesis of N-N axially chiral compounds by phase-transfer catalysis. A wide range of N-N axially chiral quinazolinone derivatives were prepared in high yields with excellent stereoselectivities. Furthermore, the synthetic utility of the protocol was proved by large-scale reaction and transformation of the product. Density functional theory calculations provide insight into the mechanism.