132898-86-3

Upstream product

• 132898-82-9 2-[(E)-2-((R)-1-Phenyl-ethylamino)-vinyl]-nicotinonitrile 
• 97308-49-1 2-trimethylsilylethynyl-3-pyridinecarbonitrile 
• 132898-81-8 2-Ethynylnicotinonitrile 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 132898-84-1 2-[2-((R)-1-Phenyl-ethylamino)-ethyl]-nicotinonitrile 

Downstream Products

• 132898-88-5 1-Methyl-6-((R)-1-phenyl-ethyl)-4,6,7,8-tetrahydro-1H-[1,6]naphthyridin-5-one 

Relevant academic research and scientific papers

Asymmetric Reductions with Freely and Non-freely Rotating Amide Group NADH Models

NADH models with a freely or a non freely rotating chiral amide group have been synthesized and used in the reduction of methyl benzoylformate.The same major enantiomer was obtained in all cases.A blocked reagent bearing a phenylalaninol group as chiral auxiliary allows one to obtain a high e.e.