132902-42-2

Basic information

• Product Name: (S)-2-(hydroxydiphenylmethyl)-1-(2'-pyridylmethyl)pyrrolidine
• Synonyms: (S)-2-(hydroxydiphenylmethyl)-1-(2'-pyridylmethyl)pyrrolidine
• CAS NO: 132902-42-2
• Molecular Weight: 344.456
• Mol File: 132902-42-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (S)-2-(hydroxydiphenylmethyl)-1-(2'-pyridylmethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(hydroxydiphenylmethyl)-1-(2'-pyridylmethyl)pyrrolidine(132902-42-2)
• EPA Substance Registry System: (S)-2-(hydroxydiphenylmethyl)-1-(2'-pyridylmethyl)pyrrolidine(132902-42-2)

Safety Data

• Hazardous Substances Data: 132902-42-2(Hazardous Substances Data)

Upstream product

• 22348-32-9 (S)-diphenylprolinol 
• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 4377-33-7 2-chloromethylpyridine 
• 31106-82-8 2-(bromomethyl)pyridine hydrobromide 
• 22348-32-9 (R)-α,α-diphenylprolinol 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 132902-37-5 (S)-2-methoxycarbonyl-1-(2-pyridylmethyl)pyrrolidine 
• 100-58-3 phenylmagnesium bromide 

Relevant articles and documents

Asymmetric henry reaction catalyzed by a chiral Cu(II) complex: A facile enantioselective synthesis of (S)-2-nitro-1-arylethanols

A catalytic asymmetric Henry reaction has been developed using a novel chiral Cu(II) complex derived from (R)-2-(diphenylmethanol)-l-(2-pyridylmethyl) pyrrolidine and copper(II) acetate in ethanol under mild conditions. The corresponding chiral 2-nitro-1-

Asymmetric Cyanosilylation of Ketones Catalyzed by Bifunctional Chiral N-Oxide Titanium Complex Catalysts

A new bifunctional catalytic system based on chiral N-oxide titanium complexes has been used for the asymmetric cyanosilylation of ketones. Screening of a variety of chiral N-oxide metal complexes resulted in (1R,2S)-1-(2'-pyridylmethyl)-2-(diphenylhydroxymethyl)pyrrolidine N-oxide titanium complex, which gave O-TMS cyanohydrins in good yields with enantiometric excesses of up to 69 percent. A catalytic cycle based on experimental phenomena and studies was proposed to explain the origin of the asymmetric induction.

Asymmetric Catalysis, Part 91: Enantioselective Monophenylation of cis-1,2-Cyclopentanediol with Triphenylbismuth Diacetate and Chiral Copper(II) Complexes as Catalysts

The monophenylation of cis-1,2-cyclopentanediol with triphenylbismuth diacetate in the presence of chiral Cu(II) complexes as catalysts gave cis-2-hydroxy-1-phenoxy-cyclopentane with enantiomeric excesses up to 38percent.The optically active ligands used were triamine derivatives of 2,6-bis(aminomethyl)pyridine and diamine derivatives of 2-(aminomethyl)pyridine.Selectivity in the monophenylation occurred only in the presence of the latter as auxiliary ligands. - Keywords.Enantioselective catalysis; Chiral Cu(II) complexes; Monophenylation; Triphenylbismuth diacetate; cis-1,2-Cyclopentanediol.