13295-95-9

Upstream product

• 19524-06-2 4-bromopyridine hydrochloride 
• 768-60-5 4-methoxyphenylacetylen 
• 1692-15-5 4-pyridylboronic acid 
• 1415665-58-5 C₂₈H₂₂Cl₂N₂O₂Pt 
• 75-05-8 acetonitrile 
• 15854-87-2 4-iodopyridine 
• 138517-17-6 Diphenyl 1-Hydroxy-1-(4-pyridyl)methanephosphonate 
• 872-85-5 pyridine-4-carbaldehyde 
• 3989-14-8 (4-methoxyphenylethynyl)trimethylsilane 
• 696-62-8 para-iodoanisole 
• 123-11-5 4-methoxy-benzaldehyde 
• 138517-18-7 diphenyl 1-chloro-1-(4-pirydyl)methanephosphonate 

Downstream Products

• 1404116-38-6 betaine 3-{4-[(4-methoxyphenyl)ethynyl]pyridinio-1-yl}-propane-1-sulfonate 
• 1415665-58-5 C₂₈H₂₂Cl₂N₂O₂Pt 
• 898564-42-6 4-(5-(4-methoxyphenyl)-1,2,3-triazol-4-yl)pyridine 
• 898564-30-2 4-(2-(pyridin-4-yl)ethynyl)phenol 
• 138517-21-2 (4-Methoxyphenyl)(4-pyridyl)acetylene N-Oxide 

Relevant academic research and scientific papers

A carrier-free and recyclable protocol for the cross-coupling of terminal alkynes with arylboronic acids in H2O/TBAB

A new and recyclable protocol was developed for Pd(OAc)2-catalyzed the cross-coupling reaction of terminal alkynes with arylboronic acids using environmentally friendly H2O/TBAB as reaction medium. A series of cross-coupling products containing internal acetylenic bond can be obtained with good selectivity and yield. The Pd(OAc)2/H2O/TBAB system was stable in the Sonogashira-type cross-coupling reaction and could be used at least three cycles without considerable decrease in catalytic performance. The results suggest that the unsupported and recyclable systems can be extended to the other realm of C&C bond formation in synthetic organic chemistry.

Two-photon-activated ligand exchange in platinum(II) complexes

Two photons are better than one: A square-planar PtII complex with derivatized pyridine ligands was synthesized (see scheme), which undergoes two-photon-induced ligand substitution with 600-740 nm light. Linear and quadratic density functional response theory allowed identification of the electronic transitions involved. Copyright

Synthesis of crown-containing and related hetarylphenylacetylenes and acetylenyl dyes

New 15(18)-crown-5(6)-containing and model methoxy-substituted 1-hetaryl-2-phenylacetylenes of the 4-pyridine and 2-benzothiazole series were synthesized using the addition of bromine to the ethylene fragment of the corresponding styrylheterocycles follow

Bicyclic Pyridinylpyrazoles

Bicyclic pyridinylpyrazoles of the formula (I) in which the symbols have the meanings given in the description and agrochemically active salts thereof and their use for controlling unwanted microorganisms in crop protection and the protection of materials

Heteroaromatic quinoline compounds

The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.

Sonogashira coupling reaction with diminished homocoupling

(Matrix presented) The side product from homocoupling reaction of two terminal acetylenes in the Sonogashira reaction can be reduced to about 2% using an atmosphere of hydrogen gas diluted with nitrogen or argon. Terminal arylethynes, diarylethynes, and a few new arylpyridylethynes with donor substituents have been synthesized in very good yields. Comparative control experiments suggest that the homocoupling yield is determined by concentration of both catalyst and oxygen.