133023-47-9Relevant articles and documents
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells
Simoni,Roberti,Invidiata,Rondanin,Baruchello,Malagutti,Mazzali,Rossi,Grimaudo,Capone,Dusonchet,Meli,Raimondi,Landino,D'Alessandro,Tolomeo,Arindam,Lu,Benbrook
, p. 2308 - 2318 (2001)
In a search for retinoic acid (RA) receptor ligands endowed with potent apoptotic activity, a series of novel arotinoids were prepared. Because the stereochemistry of the C9-alkenyl portion of natural 9-cis-RA and the olefinic moiety of the previously syn
