92654-79-0

Basic information

• Product Name: 5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENECARBALDEHYDE
• Synonyms: 5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENECARBALDEHYDE;5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbaldehyde;5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde
• CAS NO: 92654-79-0
• Molecular Formula: C₁₅H₂₀O
• Molecular Weight: 216.32
• Mol File: 92654-79-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 51-53 °C
• Boiling Point: 309.6±31.0 °C(Predicted)
• Appearance: /
• Density: 0.962±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENECARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENECARBALDEHYDE(92654-79-0)
• EPA Substance Registry System: 5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENECARBALDEHYDE(92654-79-0)

Safety Data

• Hazardous Substances Data: 92654-79-0(Hazardous Substances Data)

Upstream product

• 2591-86-8 N-Formylpiperidine 
• 27452-17-1 6-bromo-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene 
• 6683-48-3 1,1,4,4,6-pentamethyl-1,2,3,4-tetrahydronaphthalene 
• 108-86-1 bromobenzene 
• 110-03-2 2,5-dimethyl-2,5-hexanediol 
• 4885-02-3 Dichloromethyl methyl ether 
• 6683-46-1 1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene 
• 108-88-3 toluene 
• 6223-78-5 2,5-dichloro-2,5-dimethyl hexane 
• 68-12-2 N,N-dimethyl-formamide 
• 166322-31-2 6-iodo-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene 

Downstream Products

• 133023-47-9 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalen-2-ylmethylamino)benzoic acid ethyl ester 
• 131776-74-4 diethyl 1-ethoxy-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)methylphosphonate 
• 131776-66-4 2-(4-Carboxyphenyl)-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)ethanone 
• 131331-94-7 N-(4-carbethoxyphenyl)-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-2-aminoethanol 
• 2561513-58-2 (R)-N-((S)-(2-(di-tert-butylphosphanyl)phenyl)(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)-N,2-dimethylpropane-2-sulfinamide 
• 119436-60-1 Methyl (E)-4-<(5,6,7,8-tetrahydro-5,5,8,8-tetramethylbenzindan-1-ylidene)methyl>benzoate 
• 119436-61-2 Methyl (Z)-4-<(5,6,7,8-tetrahydro-5,5,8,8-tetramethylbenzindan-1-ylidene)methyl>benzoate 
• 119435-97-1 (5,6,7,8-Tetrahydro-5,5,8,8-tetramethylbenzindan-1-yl)triphenylphosphonium bromide 

Relevant articles and documents

Benzocarbazoles dioxane derivatives, its preparation process and its use in medicine

The invention relates to a benzodioxane derivative, a preparation method thereof and application of the derivative in medicines. Specifically, the invention relates to a novel benzodioxane derivative shown as a formula (I), medial salt thereof or a medicine composition containing the derivative, and a preparation method of the derivative. The invention further relates to a use of the benzodioxane derivative and the medial salt thereof or the medicine composition containing the derivative in preparing therapeutic agent, especially GPR 40 agonist, and a drug for treating the diseases such as diabetes, metabolic disorders and the like, wherein each substituent group in the formula (I) is as defined in the description.

INHIBITORS OF SPHINGOSINE KINASE

The present invention relates to compounds of the formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12,

THERAPEUTIC DRUG FOR ADULT T-CELL LEUKEMIA

An object is to provide a novel therapeutic drug for adult T-cell leukemia having an ATL cell specific antitumor effect. The therapeutic drug for adult T-cell leukemia according to the invention is characterized by containing a compound represented by the formula I or a prodrug thereof, wherein R1 is H, OH, an alkoxy group, an acyl group, or a thioacyl group, R2 is an acyl group, a thioacyl group, CONR7R8, or CSNR7R8 (R7 and R8 being each independently H, an alkyl group containing 1 to 3 carbon atoms, or a phenyl group), or R1 and R2 together may form a ring, X1 and X2 may be the same or different and are each —CR3R4—, —SiR3R4— or oxygen, and R3 and R4 may be the same or different and are each an alkyl group containing 1 to 6 carbon atoms.