133044-32-3

Basic information

• Product Name: 2(3H)-Benzothiazolone, 6-benzoyl-3-methyl-
• CAS NO: 133044-32-3
• Molecular Formula: C15H11NO2S
• Molecular Weight: 269.324
• Mol File: 133044-32-3.mol

Chemical Properties

• CAS DataBase Reference: 2(3H)-Benzothiazolone, 6-benzoyl-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Benzothiazolone, 6-benzoyl-3-methyl-(133044-32-3)
• EPA Substance Registry System: 2(3H)-Benzothiazolone, 6-benzoyl-3-methyl-(133044-32-3)

Safety Data

• Hazardous Substances Data: 133044-32-3(Hazardous Substances Data)

Upstream product

• 2786-62-1 3-methyl-(3H)benzothiazolone 
• 93-97-0 benzoic acid anhydride 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 

Downstream Products

• 135792-89-1 3-METHYL-6-Benzylbenzothiazolinone 
• 133044-56-1 3-Methyl-6-(1-Hydroxy-1-Phenylmethyl)Benzothiazolinone 
• 912266-40-1 5-benzoyl-2-methylaminothiophenol 

Relevant articles and documents

FeCl3-DMF complex as efficient catalyst for the synthesis of 6-acyl-2(3H)-benzoxazolones and 6-acyl-2(3H)-benzothiazolones

FeCl3-DMF complex has been tested on Friedel-Crafts reaction of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone with acid chlorides and anhydrides as acylating agents. In these conditions, the 6-acyl-2(3H)-benzoxazolones and 6-acyl-2(3H)-benzothiazolones were obtained in yields ranging from 52 to 89%. Among the various commonly catalysts; AlCl3-DMF, ZnCl2-DMF and PPA, explored in this study, the best conditions using FeCl3-DMF were found the most convenient one

New imidazole derivatives of 2(3H)-benzazolones as potential antifungal agents

A series of new imidazole derivatives containing 2(3H)-benzoxazolone or 2(3H)-benzothiazolone ring were synthesized as analogues of the antifungal drug bifonazole. All compounds were tested in vitro against Candida albicans, Candida parapsilosis, and Cand

Aromatase inhibitor compounds and uses thereof

The invention concerns the use of a compound of formula (I) inhibitor of aromatase for the preparation of a pharmaceutical formulation intended for treatment of cancer or psoriasis. It equally relates to compounds of formula (I), notably for their use as active ingredients of a medication.

Synthesis of 6- and 7-acyl-4H-benzothiazin-3-ones

Synthesis of 6- and 7-substituted benzoxazin-3-ones was already described in the literature by acylation of the corresponding benzoxazin-3-ones or cyclization of the corresponding 4- or 5-acyl-2-aminophenols. This paper describes original synthetic pathwa

Unsymmetrical Diarylketones from Electron-rich Heterocyclic Arenes

AlCl3-mediated chlorocarbonylation of a first arene by oxalyl chloride followed by in situ Friedel-Crafts acylation of a second electron-rich arene expeditiously provides, in a one-pot procedure, either symmetrical or unsymmetrical benzophenones with yields ranging from 17-52%. Best results are obtained when the more activated substrate is used as the second arene. Another advantage is that the resultant benzophenone precipitates from the reaction mixture allowing facile workup.

Study of the acylation reaction of 2(3H)-benzothiazolones in the mixture of ZnCl2-DMF

The use of polyphosphoric acid and the complex AlCl3-DMF in 6-acylation of 2(3H)-benzothiazolones previously have been reported. Instead of the frequently used AlCl3 as a catalyst in the Friedl-Crafts reactions, we conducted the acyl

Benzoylation of 2(3H)-benzothiazolones in the presence of 8 equivalents of zinc chloride in N,N-dimethylformamide

The use of the mixture of aluminum chloride-N,N-dimethylformamide1,2 (AlCl3-DMF, 11:1) reagent in the Friedl-Crafts C acylation reaction of 2(3H)-benzothiazolones was previously reported3. These acylations reactions were f

Benzazoles. 2. Relative activity of catalysts and 4-substituted benzoyl chlorides in the acylation of benzothiazolin-2-ones

A series has been established for the relative activity of catalysts and 4-substituted benzoyl chlorides on acylation of benzothiazolin-2-ones with 4-substituted benzoyl chlorides in the presence of FeCl3, FeCl3·6H2O, FeCl3·12H2O, ZnCl2, ZnCl2·2H2O, AlCl3, and iron acetylacetonate, as a function of the degree of acidity of the catalyst and the electrophilicity of the acylating agent.

Benzothiazolinone compounds

Compounds of general formula (I): STR1 in which: R1 represents a hydrogen atom or a lower alkyl group, R2 represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstitute