13309-95-0Relevant articles and documents
Bender,Silver
, p. 3006,3007 (1963)
Acetalization of carbonyl compounds catalyzed by bismuth triflate under solvent-free conditions
Aliyan, Hamid,Fazaeli, Razieh,Massah, Ahmad Reza,Momeni, Ahmad Reza,Naghash, Hamid Javaherian,Moeinifard, Behzad
experimental part, p. 873 - 876 (2012/04/05)
Carbonyl compounds were converted to the corresponding 1,3-dioxolanes and 1,3-dioxanes with ethylene glycol and 1,3-propandiol in the presence of bismuth triflate under solvent-free conditions. In addition, high chemoselective protection of aldehydes in the presence of ketones has been achieved.
The discovery and preparation of disubstituted novel amino-aryl-piperidine- based renin inhibitors
Cody, Wayne L.,Holsworth, Daniel D.,Powell, Noel A.,Jalaie, Mehran,Zhang, Erli,Wang, Wei,Samas, Brian,Bryant, John,Ostroski, Robert,Ryan, Michael J.,Edmunds, Jeremy J.
, p. 59 - 68 (2007/10/03)
Recently, trans-disubstituted oxo-aryl-piperidines have been identified as small molecule nonpeptide renin inhibitors for the modulation of hypertension. Herein, we report on the discovery and preparation of a new class of novel cis-disubstituted amino-aryl-piperidines as a mixture of enantiomers that are potent in vitro renin inhibitors and also, possess in vivo antihypertensive activity in a double transgenic mouse model.
Piperidine derivative rennin inhibitors
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Page/Page column 20, (2010/02/08)
Disclosed are piperidine derivatives, their manufacture and use as inhibitors of renin.