133100-90-0

Basic information

• Product Name: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(methyl phosphor-N,N-diisopropylamidite)-α,α,α-trifluorothymidine
• Synonyms: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(methyl phosphor-N,N-diisopropylamidite)-α,α,α-trifluorothymidine
• CAS NO: 133100-90-0
• Molecular Weight: 775.759
• Mol File: 133100-90-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(methyl phosphor-N,N-diisopropylamidite)-α,α,α-trifluorothymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(methyl phosphor-N,N-diisopropylamidite)-α,α,α-trifluorothymidine(133100-90-0)
• EPA Substance Registry System: 5'-O-(4,4'-dimethoxytrityl)-3'-O-(methyl phosphor-N,N-diisopropylamidite)-α,α,α-trifluorothymidine(133100-90-0)

Safety Data

• Hazardous Substances Data: 133100-90-0(Hazardous Substances Data)

Upstream product

• 70-00-8 2'-deoxy-5-trifluoromethyluridine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 125348-17-6 N,N-diisopropylmethylphosphonamidic chloride 
• 133128-06-0 5'-O-(4,4'-dimethoxytrityl)-α,α,α-trifluorothymidine 

Relevant articles and documents

Synthesis, Annealing Properties, 19F NMR Characterization, and Detection Limits of a Trifluorothymidine-Labeled Antisense Oligodeoxyribonucleotide 21 mer

The synthesis and characterization are described of trifluorothymidine groups incorporated into an antisense 21 mer designed to target gene sequences that encode serine proteases in T-lymphocytes. 1H NMR titration studies on 3',5'-O-TPDS-trifluorothymidin