133148-95-5Relevant articles and documents
Synthetic studies toward the partial ergot alkaloid LY228729, a potent 5HT(1A) receptor agonist
Carr,Creviston,Hutchison,Kennedy,Khau,Kress,Leanna,Marshall,Martinelli,Peterson,Varie,Wepsiec
, p. 8640 - 8653 (2007/10/03)
Synthetic studies on LY228729 (3) afforded two innovative approaches for the construction of this class of partial ergoline 5HT(1a) receptor agonists. The first synthesis is based upon a diastereoselective epoxidation of racemic olefin 5, followed by ring
PREPARATION OF 1-BENZOYL-4-(AMINO)-1,2,2a,3,4,5-HEXAHYDROBENZINDOLES FROM L-TRYPTOPHAN
Varie, David L.
, p. 7583 - 7586 (2007/10/02)
Acid 6a, derived from L-tryptophan, has been shown to be a useful precursor to partial ergot structures such as 3.Optically pure amine (+)-13, a key intermediate in the synthesis of 3, was prepared in 45percent overall yield from 6a via a four step sequen