133162-86-4

Upstream product

• 129886-97-1 2,4,4-Trimethyl-3a,9b-dihydro-4H-chromeno[4,3-d]oxazole-8-carbonitrile 
• 128360-08-7 N-((3R,4S)-6-Cyano-3-hydroxy-2,2-dimethyl-chroman-4-yl)-acetamide 

Downstream Products

• 340321-06-4 (4aR,10aR)-10,10-Dimethyl-4-(2-nitro-benzenesulfonyl)-2,3,4,4a,10,10a-hexahydro-1,9-dioxa-4-aza-phenanthrene-6-carbonitrile 
• 205312-12-5 (3'R,4'R)-N-(6-cyano-3,4-dihydro-2,2-dimethyl-3-hydroxy-2H-[1]benzopyran-4-yl)-2-nitrobenzenesulfonamide 

Relevant academic research and scientific papers

The action of diethylaminosulphur trifluoride (dast) on trans-4-amido- 3-Chromanols: Preparation of cis-amidoalcohols via oxazolines

Treatment of a variety of trans -4-amido-3-chromanols (3) with DAST gives oxazolines (4) which can be hydrolysed to give the corresponding cis-amido-alcohols (5). Similar treatment of the trans-4-ureido-3-chromanol (8) gave the unexpected 4-fluoro-3-ureid

Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents

A new method for the treatment of ischemic conditions and arrhythmia is disclosed. The method uses compounds of the formula STR1 wherein A can be --CH2 --, --O--, --NR9 --, --S--, --SO--, --SO2 --; X can be oxygen or sulfu