
Tetrahedron Letters p. 3649 - 3652 (1990)
Update date:2022-08-04
Topics:
Burrell, Gordon
Evans, John M.
Jones, Graham E.
Stemp, Geoffrey
Treatment of a variety of trans -4-amido-3-chromanols (3) with DAST gives oxazolines (4) which can be hydrolysed to give the corresponding cis-amido-alcohols (5). Similar treatment of the trans-4-ureido-3-chromanol (8) gave the unexpected 4-fluoro-3-ureid
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