1332356-03-2Relevant academic research and scientific papers
Design, synthesis and in vitro biochemical activity of novel amino acid sulfonohydrazide inhibitors of MurC
Frlan, Rok,Kovas, Andreja,Blanot, Didier,Gobec, Stanislav,Pecar, Slavko,Obreza, Ales
, p. 295 - 310 (2012/04/23)
Mur ligases are essential enzymes involved in the cytoplasmic steps of peptidoglycan synthesis which remain attractive, yet unexploited targets. In order to develop new antibacterial agents, we have designed a series of new MurC and MurD inhibitors bearin
