1332391-11-3Relevant articles and documents
Alluzole intermediate and method for preparing
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Paragraph 0093-0097, (2021/09/21)
The invention relates to an intermediate and a preparation method thereof, and adopts a compound as shown in a formula (4). For the preparation of, 4 is R in the formula (- COOR). 1 Or CONH2 , R1 Alkyl or aryl. The compound represented by the formula (4) is represented by the formula (3). Reaction of acyl chloride with acylating agent The acid chloride is then reacted with the thiocyanide to form. To the application, a new material formula (4) is used as an intermediate to synthesize the, and a brand new process route for synthesizing the is developed, and the process route is good in stability and good in repeatability, and is very suitable for industrial production.