1332483-72-3

Upstream product

• 134435-27-1 (2-bromo-3-methoxyphenyl)diphenylphosphine oxide 
• 1590438-82-6 1-bromo-2-(diphenylphosphinoyl)-4-methoxybenzene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 62336-24-7 (2-bromophenyl)diphenylphosphane 
• 74447-76-0 2-bromo-4'-methoxy-1,1'-biphenyl 
• 644-97-3 Dichlorophenylphosphine 
• 1332483-61-0 (4'-methoxybiphenyl-2-yl)phenylphosphine oxide 

Relevant academic research and scientific papers

Electrosynthesis of Phosphacycles via Dehydrogenative C-P Bond Formation Using DABCO as a Mediator

The first electrochemical synthesis of diarylphosphole oxides (DPOs) was achieved under mild conditions. The practical protocol employs commercially available and inexpensive DABCO as a hydrogen atom transfer (HAT) mediator, leading to various DPOs in moderate to good yields. This procedure can also be applied to the synthesis of six-membered phosphacycles, such as phenophosphazine derivatives. Mechanistic studies suggested that the reaction proceeds via an electro-generated phosphinyl radical.

Synthesis of Dibenzophospholes by Tf2O-Mediated Intramolecular Phospha-Friedel-Crafts-Type Reaction

A Tf2O-mediated intramolecular phospha-Friedel-Crafts-type reaction of secondary biarylphosphine oxides has been developed. The reaction is promoted simply by Tf2O to form the corresponding dibenzophospholes under metal-free conditio

Catalytic Synthesis of Chiral Phosphole Oxides via Desymmetric C-H Arylation of o -Bromoaryl Phosphine Oxides

A palladium-catalyzed intramolecular direct arylation reaction of o -bromoaryl phosphine oxides was developed to afford a variety of P-stereogenic phosphole oxides in good yields. The enantioselectivities were closely associated with the specific structures of substrates, which ranged from 4-94%. As a result of ready availability of starting materials and simple operation to improve the enantioselectivities of the products with low ee values, the method provides a simple and straightforward procedure for the synthesis of P-stereogenic phosphole oxides.

Synthesis of dibenzophosphole oxides via palladium-catalyzed intramolecular direct arylation reactions of ortho-halodiarylphosphine oxides

A palladium-catalyzed intramolecular direct arylation reaction was developed and two efficient one-pot sequential direct arylation/Suzuki-Miyaura coupling and intra/intermolecular direct arylation reations were also realized. The method provides a simple and straightforward procedure for the synthesis and further functionalization of dibenzophosphole oxides from easily accessible ortho-halodiarylphosphine oxides in good to excellent yields.

Palladium-catalyzed direct synthesis of phosphole derivatives from triarylphosphines through cleavage of carbon-hydrogen and carbon-phosphorus bonds

(Phosp)hole in one: A palladium-catalyzed synthesis for directly assembling phosphole skeletons from triarylphosphines through C-H and C-P bond cleavage was developed. This approach overcomes several of the limitations of the so far reported methods. Phospholes bearing a range of functionalities (including Br, F, CO2Me, Ac, and CN) and an array of fused rings (naphthalenes, anthracenes, furans, and pyrroles) can be easily synthesized. Copyright

Palladium-catalyzed synthesis of dibenzophosphole oxides via intramolecular dehydrogenative cyclization

Dibenzophosphole oxides were obtained from secondary hydrophosphine oxides with a biphenyl group by dehydrogenation via phosphine-hydrogen and carbon-hydrogen bond cleavage in the presence of a catalytic amount of palladium(II) acetate, Pd(OAc)2/sub