1332724-93-2Relevant academic research and scientific papers
BIS-(ARYL/HETEROARYL)-METHYLENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND THEIR USE FOR TREATING CANCER
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, (2013/07/05)
The present disclosure relates to novel bis-(aryl/heteroaryl)-methylene compounds of formula (I) having vitamin D receptor agonist and histone deacetylase (HDAC) inhibitory efficacy as well as to methods for reducing or inhibiting the proliferation of can
Novel nonsecosteroidal vitamin D3 carboxylic acid analogs for osteoporosis, and SAR analysis
Kashiwagi, Hirotaka,Ono, Yoshiyuki,Shimizu, Kazuki,Haneishi, Tsuyoshi,Ito, Susumu,Iijima, Shigeyuki,Kobayashi, Takamitsu,Ichikawa, Fumihiko,Harada, Suguru,Sato, Hideki,Sekiguchi, Nobuo,Ishigai, Masaki,Takahashi, Tadakatsu
experimental part, p. 4721 - 4729 (2011/10/04)
Novel vitamin D3 analogs with carboxylic acid were explored, focusing on a nonsecosteroidal analog, LG190178, with a bisphenyl skeleton. From X-ray analysis of these analogs with vitamin D receptor (VDR), the carboxyl groups had very unique hyd
