133286-18-7Relevant academic research and scientific papers
Direct Synthesis of 4-Quinolones via Copper-Catalyzed Anilines and Alkynes
Xu, Xuefeng,Zhang, Xu
supporting information, p. 4984 - 4987 (2017/09/22)
A unique and direct approach for constructing 4-quinolones from simple and readily available anilines and alkynes is described. Under the optimal conditions, both N-alkyl- and N-aryl-substituted anilines can be successfully transformed into the corresponding 4-quinolones. This reaction is characterized by mild reaction conditions, high functional-group tolerance, and amenability to gram-scale synthesis.
ZnCl2-catalyzed intramolecular cyclization reaction of 2-aminochalcones using polymer-supported selenium reagent: Synthesis of 2-phenyl-4-quinolones and 2-phenyl-2,3-dihydroquinolin-4(1 H)-one
Tang,Chen, Bangzheng,Zhang, Lianpeng,Li, Wen,Lin, Jun
experimental part, p. 707 - 711 (2011/04/26)
A new and efficient method for the synthesis of 2-phenyl-4-quinolones and 2-phenyl-2,3-dihydroquinolin-4(1H)-ones is described. The reaction involves ZnCl2-mediated polystyrene-supported selenium-induced intramolecular cyclization of 2-amino-chalcones and subsequent traceless or functionalizing cleavage of selenium linker. Georg Thieme Verlag Stuttgart - New York.
Syntheses of chromones and quinolones via Pd-catalyzed carbonylation of o-iodophenols and anilines in the presence of acetylenes
Torii, Sigeru,Okumoto, Hiroshi,Xu, Long He,Sadakane, Masahiro,Shostakovsky, Michel V.,Ponomaryov, Andrew B.,Kalinin, Valery N.
, p. 6773 - 6784 (2007/10/02)
Synthesis of 2-substituted chromones and quinolones has been performed by a Pd-catalyzed carbonylation of o-iodophenols or o-iodoanilines in the presence of terminal acetylenes in a high yield through coupling of halides and acetylenes followed by cyclization as a one-pot reaction.
Palladium-catalyzed carbonylation to form 2-substituted 1,4-dihydro-4-oxo-quinoline
Torii, Sigeru,Okumoto, Hiroshi,Xu, Long He
, p. 237 - 240 (2007/10/02)
Palladium-catalyzed carbonylation of 2-haloaniline in the presence of terminal acetylenes under proper conditions (20 Kgcm-2 of CO at 120°C) gave a variety of 2-substituted 1,4-dihydro-4-oxo-quinolines in good yields.
