1333111-32-2Relevant academic research and scientific papers
N-substituted [phenyl-pyrazolo]-oxazin-2-thiones as COX-LOX inhibitors: Influence of the replacement of the oxo -group with thioxo- group on the COX inhibition activity of N-substituted pyrazolo-oxazin-2-ones
Bennamane, Nora,Nedjar-Kolli, Bellara,Geronikaki, Athina A.,Eleftheriou, Phaedra Th.,Kaoua, Rachedine,Boubekeur, Kamal,Hoffman, Pascal,Chaudhary, Shailendra S.,Saxenaf, Anil K.
, (2011/05/06)
Targeting to the synthesis of potent dual acting COX/LOX inhibitors as future anti-inflammatory drugs, we attempted a modification of the compounds based on docking analysis results. A substitution of the oxygen of the oxo-group of the oxazin-2-one ring b
