1333145-70-2Relevant academic research and scientific papers
Total synthesis and cytotoxicity evaluation of an oxazole analogue of tubulysin U
Shankar, P. Sreejith,Sani, Monica,Saunders, Fiona R.,Wallace, Heather M.,Zanda, Matteo
, p. 1673 - 1676 (2011/09/15)
Tubulysins are strongly cytotoxic natural tetrapeptides with potent antiproliferative, antimitotic, and antiangiogenic activities which might find use in oncology. We herein report the first total synthesis of a stereoisomerically pure oxazole analogue of
