1333193-92-2Relevant academic research and scientific papers
Practical synthesis of diethyl phenylsuccinate by Mg-promoted carboxylation of ethyl cinnamate
Maekawa, Hirofumi,Murakami, Taro,Miyazaki, Takeshi,Nishiguchi, Ikuzo
, p. 368 - 369 (2011)
Mg-promoted reduction of ethyl cinnamate (1a) in the presence of carbon dioxide gave a mixture of β-carboxylated compound 2a and α,β-dicarboxylated compound 3a. Similar reductive carboxylation of 1a followed by acidic decarboxylation of one of the two geminal carboxyl groups of the generated 3a and esterification afforded selective formation of diethyl phenylsuccinate (2a) in good yield.
