1333325-95-3Relevant academic research and scientific papers
Synthetic utilization of 2-chloro-1,1,1,2-tetrafluoroethane
Notsu, Keiji,Zushi, Yasuyuki,Ota, Shin,Kawasaki-Takasuka, Tomoko,Yamazaki, Takashi
, p. 9200 - 9208 (2011/09/19)
β-Substituted α-fluoro-α,β-unsaturated carboxylic acids have been successfully synthesized, usually in a (Z)-stereospecific manner by way of a stepwise or a one-pot three-step procedure starting from 2-chloro-1,1,1,2-tetrafluoroethane (HCFC-124), one of the major byproducts of the industrial process for tetrafluoroethene formation from chlorofluoromethane (HCFC-22). Get some Z's! β-Substituted α-fluoro-α,β- unsaturated carboxylic acids have been successfully synthesized from 2-chloro-1,1,1,2-tetrafluoroethane, one of the major byproducts of tetrafluoroethene formation from chlorofluoromethane. The products are usually obtained with Z stereoselectivity, by either a stepwise or a one-pot three-step procedure (see scheme).
