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1-(3H-benzo[d]imidazol-4-yl)-5-(benzyloxy)-2-methylpyridin-4(1H)-one, also known as BI 224436, is a complex chemical compound featuring a benzimidazole ring, a benzyloxy group, and a pyridinone ring. It is a kinase inhibitor with a molecular weight of 368.39 g/mol, which has demonstrated potential in the field of cancer treatment by targeting specific kinases that play a role in cancer cell proliferation. The unique structure and promising medicinal properties of 1-(3H-benzo[d]imidazol-4-yl)-5-(benzyloxy)-2-methylpyridin-4(1H)-one make it a significant subject for ongoing research and development in the pharmaceutical industry.

1333331-92-2

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1333331-92-2 Usage

Uses

Used in Pharmaceutical Industry:
1-(3H-benzo[d]imidazol-4-yl)-5-(benzyloxy)-2-methylpyridin-4(1H)-one is used as a kinase inhibitor for its potential role in cancer treatment. It targets specific kinases involved in the proliferation of cancer cells, thereby inhibiting their growth and contributing to the development of novel therapeutic strategies against various types of cancer.
Additionally, due to its potential medicinal uses, 1-(3H-benzo[d]imidazol-4-yl)-5-(benzyloxy)-2-methylpyridin-4(1H)-one may also be utilized in:
Drug Discovery and Development: As a lead compound in the development of new drugs targeting kinase-related pathways in cancer and other diseases.
Preclinical Research: For evaluating the efficacy and safety of BI 224436 in various cancer models before advancing to clinical trials.
Target Identification and Validation: To understand the specific kinases and pathways that 1-(3H-benzo[d]imidazol-4-yl)-5-(benzyloxy)-2-methylpyridin-4(1H)-one interacts with, providing insights into its mechanism of action and potential applications in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 1333331-92-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,3,3,3 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1333331-92:
(9*1)+(8*3)+(7*3)+(6*3)+(5*3)+(4*3)+(3*1)+(2*9)+(1*2)=122
122 % 10 = 2
So 1333331-92-2 is a valid CAS Registry Number.

1333331-92-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(1H-benzimidazol-4-yl)-5-(benzyloxy)-2-methylpyridin-4(1H)-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:1333331-92-2 SDS

1333331-92-2Downstream Products

1333331-92-2Relevant academic research and scientific papers

INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS

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, (2011/10/03)

The present invention relates to 4-pyridinone compounds which are inhibitors of catechol O-methyltransferase (COMT), and are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which COMT enzyme is involved. The present invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which COMT is involved

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