1333413-08-3Relevant academic research and scientific papers
Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2′-C-piperazino-UNA monomer
Jensen, Troels B.,Henriksen, Jonas R.,Rasmussen, Bjarne E.,Rasmussen, Lars M.,Andresen, Thomas L.,Wengel, Jesper,Pasternak, Anna
, p. 4739 - 4745 (2011)
Thrombin binding aptamer is a DNA 15-mer which forms a G-quadruplex structure and possess promising anticoagulant properties due to specific interactions with thrombin. Herein we present the influence of a single 2′-C-piperazino-UNA residue and UNA residu
