1333466-54-8

Basic information

• Product Name: 4-N-(benzyl-5-hydroxymethyl)cytosine
• Synonyms: 4-N-(benzyl-5-hydroxymethyl)cytosine
• CAS NO: 1333466-54-8
• Molecular Weight: 231.254
• Mol File: 1333466-54-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-N-(benzyl-5-hydroxymethyl)cytosine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-(benzyl-5-hydroxymethyl)cytosine(1333466-54-8)
• EPA Substance Registry System: 4-N-(benzyl-5-hydroxymethyl)cytosine(1333466-54-8)

Safety Data

• Hazardous Substances Data: 1333466-54-8(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 5785-16-0 N⁴-benzylcytosine 
• 1346635-30-0 C₁₁H₉N₃O 
• 100-52-7 benzaldehyde 

Downstream Products

• 1333466-55-9 4-N-(benzyl-5-acetyloxymethyl)cytosine 
• 1400898-71-6 4-N-benzylcytosine 5-methylsulfonic acid sodium salt 

Relevant articles and documents

CYTOSINE ANALOGUE, A METHOD OF PREPARATION OF A CYTOSINE ANALOGUE, A DNA METHYLTRANSFERASE 1 INHIBITOR, A METHOD FOR DNA METHYLATION INHIBITION, THE USE OF THE ANALOGUE IN THE TREATMENT OF DISEASES ASSOCIATED WITH DEVIATIONS FROM NORMAL DNA METHYLATION

This invention provides a cytosine analogue, a method of preparation of a cytosine analogue, a DNA rhethyltransferase 1 inhibitor, a method for DNA methylation inhibition, the use of the analogue in the treatment of diseases associated with deviations from normal DNA methylation. More precisely, the invention relates to various derivatives of cytosine, as well as methods of preparation of mono- and multi-1,4,5 and 6-substituted cytosines. In general, the solution relates to providing effective modulators of DNA methylation which could be used in prevention and treatment of diseases associated with DNA methylation level disorders.

A CYTOSINE ANALOGUE, A METHOD OF PREPARATION OF A CYTOSINE ANALOGUE, A DNA METHYLTRANSFERASE 1 INHIBITOR, A METHOD FOR DNA METHYLATION INHIBITION, THE USE OF THE ANALOGUE IN THE TREATMENT OF DISEASES ASSOCIATED WITH DEVIATIONS FROM NORMAL DNA METHYLATION

This invention provides a cytosine analogue, a method of preparation of a cytosine analogue, a DNA rhethyltransferase 1 inhibitor, a method for DNA methylation inhibition, the use of the analogue in the treatment of diseases associated with deviations from normal DNA methylation. More precisely, the invention relates to various derivatives of cytosine, as well as methods of preparation of mono- and multi- 1,4,5 and 6-substituted cytosines. In general, the solution relates to providing effective modulators of DNA methylation which could be used in prevention and treatment of diseases associated with DNA methylation level disorders.