133382-26-0

Upstream product

• 687-47-8 (S)-Ethyl lactate 
• 14378-06-4 (E)-α-cyanocinnamic acid 

Downstream Products

• 162272-48-2 (S)-Ethyl lactate (1S,6R)-1-cyano-6-phenyl-3-cyclohexene-1-carboxylate 
• 144846-59-3 methyl (1S,6R)-1-cyano-3,4-dimethyl-6-phenyl-3-cyclohexen-1-carboxylate 
• 142698-01-9 (1S,2S,3R,4R,5R,6R)-2-exo-cyano-6-endo-hydroxy-5-exo-iodo-3-exo-phenylbicyclo<2.2.1>heptane-2-endo-carboxylic acid lactone 
• 1026501-96-1 (1S,2R)-1-Cyano-2-phenyl-cyclohexanecarbonyl azide 
• 162272-57-3 Methyl (1R,2R)-1-isocyanato-2-phenyl-1-cyclohexanecarboxylate 
• 162272-55-1 Methyl (1S,2R)-1-(aminocarbonyl)-2-phenyl-1-cyclohexanecarboxylate 
• 1026878-49-8 (1S,2R)-1-Cyano-2-phenyl-1-cyclohexanecarboxylic acid chloride 
• 162272-51-7 (1S,2R)-1-Cyano-2-phenyl-1-cyclohexanecarboxylic acid 
• 165674-42-0 Methanesulfonic acid (1S,2R)-1-cyano-2-phenyl-cyclohexylmethyl ester 
• 165674-43-1 (1R,2R)-1-Azidomethyl-2-phenyl-cyclohexanecarbonitrile 
• 165674-39-5 (1S,2R)-methyl 1-aminomethyl-2-phenyl-1-cyclohexanecarboxylate 
• 165674-40-8 (1S,2R)-1-hydroxymethyl-2-phenyl-1-cyclohexanecarbonitrile 
• 165674-44-2 (1R,2S)-1-aminomethyl-2-phenyl-1-cyclohexanecarbonitrile 
• 162272-56-2 Methyl (1S,2R)-1-cyano-2-phenyl-1-cyclohexanecarboxylate 

Relevant academic research and scientific papers

Reaction of cyclopentadiene with (E)-2-cyanocinnamate of (S)-ethyl lactate

The model proposed by Helmchen explains the results obtained in the reaction of 1 chiral dienophile with cyclopentadiene in the presence of TiCl4 or in non-catalyzed reactions, but when AlCl2Et is used, the results are unexpected. A

Reaction of 2,3-Dimethyl-1,3-Butadiene with Chiral (E)-2-Cyanocinnamates.

The reactions of 2,3-dimethyl-1,3-butadiene with (E)-2-cyanocinnamates of (S)-ethyl lactate (1a) and (R)-pantolactone (1b), catalysed by TiCl4, afford enantiomerically pure cycloadducts which are easily converted into enantiomers (1R, 6S) and (1S, 6R) of

Asymmetric Diels-Alder Reactions of Chiral (E)-2-Cyanocinnamates with Cyclopentadiene

Several chiral derivatives of (E)-2-cyanocinnamic acid are used as trisubstituted dienophiles, and their asymmetric Diels-Alder reactions with cyclopentadiene are studied.The reactions of (E)-2-cyanocinnamates of (S)-ethyl lactate and (R)-pantolactone wit